Zahra Lotfollahi
PhD in Solis state Physics, University of Birjand, Brazil.
Title: dentalhealth-ann-2020
Biography
Biography: Zahra Lotfollahi
Abstract
The objective of the present study was to establish if individuals with DiabetesMellitus (DM2) and
periodontal diseases (periodontitis and gingivitis) presented an increase in the concentration of modified LDL (moLDL) and what is the influence of periodontal treatment on the decrease of moLDL particles with consequent improvement in the parameters of DM2. Twenty-four diabetic patients with periodontitis (Group 1) and gingivitis (Group 2) were followed up for 12 months. Group 1 was treated with periodontal debridement, and Group 2 received supragingival scaling and prophylaxis. In both groups, periodontal clinical parameters: probing depth (PD), clinical attachment level (CAL), gingival resection (GR), bleeding on probing index (BOP) and plaque index; inflammatory serum markers (glycemia, A1c, TC, HDL-c, LDL-c, TG and hs-CRP) and oxLDL were measured at baseline, t = 6 and t = 12 months after treatment. Solutions of LDL were analyzed using the nonlinear optical Z-Scan and absorption techniques. The periodontal clinical parameters showed significant improvement in both Group after 12 months. For both groups, TC, HDL-c, LDLc, TG and A1c levels did not show significant reductions after periodontal therapy. hs-CRP levels in Group 1 presented a significant reduction after 12 months. The glycemic rate and the oxLDL concentrations did not show significant differences as a function of time. The optical measurements of LDL solutions revealed an improvement of the LDL-c quality in both groups. Periodontal debridement was able to improve periodontal parameters and the quality of LDL-c in diabetic patients but without changes in the oxLDL concentration in both groups.
The objective of the present study was to establish if individuals with DiabetesMellitus (DM2) and
periodontal diseases (periodontitis and gingivitis) presented an increase in the concentration of modified LDL (moLDL) and what is the influence of periodontal treatment on the decrease of moLDL particles with consequent improvement in the parameters of DM2. Twenty-four diabetic patients with periodontitis (Group 1) and gingivitis (Group 2) were followed up for 12 months. Group 1 was treated with periodontal debridement, and Group 2 received supragingival scaling and prophylaxis. In both groups, periodontal clinical parameters: probing depth (PD), clinical attachment level (CAL), gingival resection (GR), bleeding on probing index (BOP) and plaque index; inflammatory serum markers (glycemia, A1c, TC, HDL-c, LDL-c, TG and hs-CRP) and oxLDL were measured at baseline, t = 6 and t = 12 months after treatment. Solutions of LDL were analyzed using the nonlinear optical Z-Scan and absorption techniques. The periodontal clinical parameters showed significant improvement in both Group after 12 months. For both groups, TC, HDL-c, LDLc, TG and A1c levels did not show significant reductions after periodontal therapy. hs-CRP levels in Group 1 presented a significant reduction after 12 months. The glycemic rate and the oxLDL concentrations did not show significant differences as a function of time. The optical measurements of LDL solutions revealed an improvement of the LDL-c quality in both groups. Periodontal debridement was able to improve periodontal parameters and the quality of LDL-c in diabetic patients but without changes in the oxLDL concentration in both groups.